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Therefore, more selective SLC7A11 inhibitors and genetic targeting strategies, including small interfering RNAs (siRNA) and small guide RNAs (sgRNA), would be ideal for clinical purposes

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5 In a study examining BPC-157's effects on in vitro wound healing using human umbilical vein endothelial cells (HUVECs), treatment with BPC-157 at concentrations of 10 -9 to 10 -7 M significantly accelerated scratch-wound closure compared to vehicle-treated controls, with accompanying increases in VEGFR2 phosphorylation the primary signaling receptor through which VEGF drives endothelial proliferation and migration

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[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Brooke D